AV-Comparatives’ 2026 Business Security Test evaluated 15 enterprise products over 4 months. CrowdStrike Falcon and SentinelOne tied for top position, both achieving 99.7% overall protection with zero false positives. Bitdefender GravityZone achieved 99.6%. ESET PROTECT and Sophos Intercept X reached 99.5%. CrowdStrike’s cloud-native architecture caused just 1.2% system slowdown while some legacy products caused 12-18%. ESET PROTECT Advanced won the performance award. FortiClient EMS demonstrated excellent network integration. Our analysis helps security managers select the right enterprise product.